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Setayeshpour, Y., Chen, SY., Dayanidhi, D.L. et al. Ascites protects against ferroptosis and enables the peritoneal growth of ovarian cancer. Nat Commun 17, 4190 (2026). https://doi.org/10.1038/s41467-026-72116-1 A newly published study in Nature Communications sheds light on an important question in ovarian cancer research: why ovarian cancer cells are often able to survive and spread throughout the abdominal cavity. Researchers from Duke University School of Medicine found

Falla-Zuniga, L.F., King, M.C., Pawlikowski, K. et al. Quality of Life After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC): Cancer Survivors’ Perspective Through In-Depth Interviews. Ann Surg Oncol 31, 7122–7132 (2024). What is this study about? This study looked at women with advanced ovarian cancer (stage III) who underwent: Cytoreductive surgery (surgery to remove as much cancer as possible) With or without HIPEC (heated chemotherapy deliv

Darling A, Harlev C, O’Cearbhaill R . Use of hyperthermic intraperitoneal chemotherapy in the treatment of ovarian cancer: A multidisciplinary review. Surgical Oncology Insight, 2026; 3 What is this study about? This article looks at a treatment called HIPEC (Hyperthermic Intraperitoneal Chemotherapy). HIPEC is given during surgery for cancers that have spread inside the abdomen (like ovarian cancer). Doctors circulate warm chemotherapy directly in the belly to kill cancer

Falla-Zuniga LF, Sardi A, King MC, Lopez-Ramirez F, Kovalik V, Iugai S, Diaz-Montes T, Gushchin V. Small bowel obstruction and ovarian cancer: insights from a propensity-score matched study in patients with and without hyperthermic intraperitoneal chemotherapy after cytoreductive surgery. World J Surg Oncol. 2025 Aug 26;23(1):318. doi: 10.1186/s12957-025-03968-y. PMID: 40859247; PMCID: PMC12382003. What was this study about? People with advanced ovarian cancer sometimes devel

Somashekhar, S.P. HIPEC in Advanced Ovarian Cancer: From Controversy to Contextual Standard of Care. Indian J Gynecol Oncolog 24 , 52 (2026). https://doi.org/10.1007/s40944-026-01122-4 What is this study about? This article looks at a treatment approach called HIPEC (hyperthermic intraperitoneal chemotherapy) for people with advanced ovarian cancer—a cancer that often spreads within the abdomen. Even with surgery and chemotherapy, many patients still have tiny cancer cells l

Falla-Zuniga LF, Sardi A, King MC, Lopez-Ramirez F, Kovalik V, Iugai S, Diaz-Montes T, Gushchin V. Small bowel obstruction and ovarian cancer: insights from a propensity-score matched study in patients with and without hyperthermic intraperitoneal chemotherapy after cytoreductive surgery. World J Surg Oncol. 2025 Aug 26;23(1):318. doi: 10.1186/s12957-025-03968-y. PMID: 40859247; PMCID: PMC12382003. Understanding the Study: Bowel Blockages in Advanced Ovarian Cancer This stu

Predictors of Successful Neoadjuvant Chemotherapy and Interval Cytoreductive Surgery in Management of Ovarian Cancer. ** Authors : Claudia Marchetti, MD, PhD, Gwenael Ferron, MD, et al. JCO Oncology Practice, Nov 24, 2025. DOI: 10.1200/OP-25-00469 Understanding Neoadjuvant Chemotherapy and Surgery What the Study Was About This study focused on individuals with ovarian cancer who receive neoadjuvant chemotherapy (NACT). This means they undergo chemotherapy before surgery. T

Efficacy and Safety of Secondary Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy in Platinum-Sensitive Recurrent Ovarian Cancer: A Systematic Review and Meta-Analysis Liu, HY., Tian, LH., Huang, G. et al. World J Surg Onc 23, 423 (2025). https://doi.org/10.1186/s12957-025-04076-7 What the Study Looked At Researchers examined data from over 1,100 individuals with platinum-sensitive recurrent ovarian cancer. This means their cancer initially responded to p

By Kristin Logan Texas October 2025 In 2023, I finally thought I had my life figured out. My only child was off to university in the...

Kristin Logan’s story is nothing short of heartbreaking—and revealing. A healthy mother, veteran, wife, and resident of British Columbia,...

In a HuffPost article about stage 4 ovarian cancer and 5-year survival, readers are introduced to Susan , a woman diagnosed with stage 4 disease whose journey challenges common expectations. The article uses Susan’s experience as a powerful example of hope and resilience, showing that while statistics are important, they don’t tell every person’s story. Susan and her husband on their wedding day in 2017. What Susan’s Journey Teaches Us A strong reminder that survival curves

During September we recognized Ovarian Cancer Awareness Month to bring more attention to advanced forms of this cancer. In case you...

A physician may use some or all of these methods to treat ovarian cancers . ​ 1️⃣ Surgery: the physical removal of all visible tumors...

A physician may use some or all of these evaluation methods to diagnose ovarian cancer . ​ 1️⃣ Physical exam 2️⃣ Imaging studies:...

Guest Authors: Travis Rodgers & Amy Edel September is both Mesothelioma and Ovarian Cancer Awareness Month. These two cancers affect the...

Signs and symptoms of ovarian cancers can be similar to other conditions and are often non-specific . ​ 1️⃣ Abdominal or pelvic...

Risk factors for ovarian cancer to be aware of include: ​ Ovarian Cancer Risk Factors: 1️⃣ Age: Commonly occurs between ages 50-60...

Mary Kathryn Abel, MD, MAS ; Varvara Mazina, MD ; Amy J. Bregar, MD; et al. JAMA Network Open; Published Online: July 25, 2025;...

OVHIPEC-1 confirms that for women with advanced ovarian cancer, combining HIPEC with cytoreductive surgery can provide a meaningful, long-term survival benefit while maintaining quality of life.

By Kelly McCarley Maryland March 2025 My name is Kelly McCarley and I am a three-time cancer survivor. I have had ovarian, peritoneal,...