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Unlocking New Possibilities for Immunotherapy for Colorectal Cancers
This study focused on a key challenge: in many bowel cancers, especially stromal-rich types (those with lots of supporting tissue, or stromal cells, around the tumor), immune therapies aren’t working as well as hoped. Researchers investigated how certain “support” cells within the tumor (called stromal cells) may be actively helping the cancer by suppressing the body’s immune system. Then they investigated how to turn the immune system back on again in these hard-to-treat can
Abdominal Cancers Alliance
1 day ago


PSOGI World News - October 2025 Newsletter
A quarterly newsletter with the latest news, views and announcements from Peritoneal Surface Oncology Group International (PSOGI) Led by pioneering surgical oncologist Dr. Paul Sugarbaker, PSOGI is a collaboration of experts from around the world on the treatment of peritoneal cancer and is dedicated to improving treatment and survival of patients with peritoneal metastases . While PSOGI World News is a quarterly publication primarily intended for healthcare professionals, t
Abdominal Cancers Alliance
Oct 13


Why Federally Funded Cancer Trials Matter, Especially for Rare Abdominal Cancers
When you hear “clinical trials,” you might think of the drug companies doing studies of new medicines. But did you know that federally funded trials—backed by government agencies—play a unique and absolutely critical role in cancer research? A recent study shows just how important they are for rare cancers, children, and complex treatment strategies.
Abdominal Cancers Alliance
Oct 8


New NCI Director Brings Hope for Rare and Abdominal Cancers Research
The National Cancer Institute (NCI) — the nation’s leading cancer research agency — has a new director. Dr. Anthony Letai officially...
Abdominal Cancers Alliance
Oct 8


Does Chemotherapy Before Surgery Help in Advanced Appendix Cancer?
Carlos A Munoz-Zuluaga , Mary Caitlin King , Panayotis Ledakis , Vadim Gushchin , Michelle Sittig , Carol Nieroda , Katherine Zambrano-Vera , Armando Sardi Systemic chemotherapy before cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) in patients with high-grade mucinous carcinoma peritonei of appendiceal origin . European Journal of Surgical Oncology. 2019 Sep;45(9):1598-1606. https://pubmed.ncbi.nlm.nih.gov/31109821/ Summary: Researche
Abdominal Cancers Alliance
Oct 7


Chemotherapy After Surgery for Advanced Appendix Cancer: Is It Needed?
Ekaterina Baron, Armando Sardi, Mary Caitlin King, Andrei Nikiforchin, Felipe Lopez-Ramirez, Carol Nieroda, Vadim Gushchin, Panayotis...
Abdominal Cancers Alliance
Oct 6


Research Spotlight: CRS + HIPEC Improves Survival in Peritoneal Mesothelioma
Serkan Yaşar MD , Feride Yılmaz MD , Güngör Utkan MD , Efnan Algın MD , Doğan Bayram, MD , Selim Tamam MD , Ömür Berna Çakmak Öksüzoğlu...
Abdominal Cancers Alliance
Sep 12


Research Spotlight: Chemo Before Surgery Improves Outcomes in Ovarian Cancer
Mary Kathryn Abel, MD, MAS ; Varvara Mazina, MD ; Amy J. Bregar, MD; et al. JAMA Network Open; Published Online: July 25, 2025;...
Abdominal Cancers Alliance
Sep 3


Research Spotlight: Cytoreductive Surgery and HIPEC Is NOT a Last Resort: Why Early Referral Matters
Leah E. Hendrick, MD , Seth Felder, MD , Iman Imanirad, MD , and Sean P. Dineen, MD, MHPE JCO Oncology Practice (Oct 2024). Volume 21,...
Abdominal Cancers Alliance
Aug 25


CRS/HIPEC Shows Long-Term Survival Benefit for Advanced Ovarian Cancer (OVHIPEC-1)
OVHIPEC-1 confirms that for women with advanced ovarian cancer, combining HIPEC with cytoreductive surgery can provide a meaningful, long-term survival benefit while maintaining quality of life.
Abdominal Cancers Alliance
Aug 15


Research Spotlight: Multicenter Study Strengthens Case for CRS/HIPEC in Peritoneal Metastases from Small Bowel Adenocarcinoma
Marco Tonello MD, PhD , Carola Cenzi MS, PhD , Elisa Pizzolato MD , Manuela Martini RN , Pierluigi Pilati MD & Antonio Sommariva MD ...
Abdominal Cancers Alliance
Jul 24


PSOGI World News - July 2025 Newsletter
A quarterly newsletter with the latest news, views and announcements from Peritoneal Surface Oncology Group International (PSOGI) Led by...
Abdominal Cancers Alliance
Jul 10


Trial of Radical Upfront Surgical Therapy (TRUST) in Advanced Ovarian Cancer
Sven Mahner, Florian Heitz, Sahar Salehi, Alexander Reuss, Frederic Guyon, Andreas du Bois, Philipp Harter, Christina Fotopoulou, Denis...
Abdominal Cancers Alliance
Jul 1


Uncovering Social Disparities in Early-Onset Colorectal Cancer
Real-world social determinants of health (SDOH) and outcomes of early-onset colorectal cancer (EO-CRC): An analysis of a large,...
Abdominal Cancers Alliance
Jun 30


Appendix Cancer Rates Rising in Younger Adults: Birth Cohort Effects in Appendiceal Adenocarcinoma Incidence Across the United States
Researchers used National Cancer Institute data to compare appendix cancer rates across generations. They found that people born in the 1980s were three to four times more likely to be diagnosed with this cancer than those born in the 1940s.
Abdominal Cancers Alliance
Jun 12


Summary of STOPGAP trial: a Phase II clinical trial for gastric and gastroesophageal junction cancers
Maheswari Senthil, Farshid Dayyani BMC Cancer This research article about the STOPGAP trial explores a new treatment approach for...
Abdominal Cancers Alliance
May 1


PSOGI World News - April 2025 Newsletter
A quarterly newsletter with the latest news, views and announcements from Peritoneal Surface Oncology Group International (PSOGI) Led by...
Abdominal Cancers Alliance
Apr 21


Ten-Year Outcome of a Randomized Trial: Cytoreduction and HIPEC with Mitomycin C Versus Oxaliplatin for Appendiceal Neoplasm with Peritoneal Dissemination
Edward A. Levine MD, Heidy Cos MD, Konstantinos I. Votanopoulos MD, PhD, Perry Shen MD, Greg Russell MS, Paul Mansfield MD, Keith...
Abdominal Cancers Alliance
Mar 31


How Prior Surgeries Affect Outcomes in Mucinous Appendix Cancer Patients Undergoing CRS/HIPEC
Sergei Iugai MD, Mary Caitlin King BS, Vladislav Kovalik MD MPSH, Luis Felipe Falla-Zuniga MD, Kseniia Uzhegova MD, Abeerah Wasti BS,...
Abdominal Cancers Alliance
Feb 28
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