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Ostowari A, Chen KT, Hasjim BJ, Montero S, Sedighim S, Tajik F, Roman M, Dayyani F, Daly S, Smith BR, Nguyen NT, Eng OS, O'Leary MP, Senthil M. Underutilization of Staging Laparoscopy Prior to Neoadjuvant Systemic Therapy in Gastric Cancer. Ann Surg Oncol. 2026 Feb;33(2):1343-1349. doi: 10.1245/s10434-025-18547-4. Epub 2025 Oct 17. PMID: 41107646; PMCID: PMC12765731. When stomach (gastric) cancer or gastroesophageal junction (GEJ) cancer is diagnosed, doctors often recommend

Brianna M. Krusen, Phyllis A. Gimotty, Greg Donahue, Jacob E. Till, Melinda Yin, Erin E. Carlson, William R. Bamlet, Erica L. Carpenter, Shounak Majumder, Ann L. Oberg, Kenneth S. Zaret; Improving a Plasma Biomarker Panel for Early Detection of Pancreatic Ductal Adenocarcinoma with Aminopeptidase N (ANPEP) and Polymeric Immunoglobulin Receptor (PIGR). Clin Cancer Res 15 February 2026; 32 (4): 756–769. https://doi.org/10.1158/1078-0432.CCR-25-3297 Why This Matters Pancreatic

Framarini M, D'Acapito F, Lippolis PV, Di Giorgio A, Di Pietrantonio D, Sommariva A, Sammartino P. Expanding the role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: A multicenter study on uncommon peritoneal malignancies. World J Clin Oncol 2025; 16(12): 112443 [PMID: 41480175 DOI: 10.5306/wjco.v16.i12.11244 3] Peritoneal metastasis is when cancer cells spread from the stomach or other organs to the lining of the abdominal cavity. This type of sprea

Matsumiya, M., Sonoda, H., Yamashita, H. et al. Intraperitoneal Paclitaxel-Induced Eosinophil Recruitment as a Potential Mediator of Tumor Response in Peritoneal Metastases from Gastric Cancer. Ann Surg Oncol (2026). https://doi.org/10.1245/s10434-025-19075-x What was studied? Researchers looked at how i ntraperitoneal chemotherapy (medicine delivered directly into the abdominal cavity) affects the immune environment in people with gastric (stomach) cancer that has spread t

Matt turned 40 with big plans. A healthier lifestyle. More time with family. But when unexpected symptoms led to a rare cancer diagnosis, everything changed. Leading up to his 40th birthday, he decided to get healthier “to be there for his wife, son, and parents.” Matt started eating better and exercising in late Spring 2019. Despite these changes, Matt began experiencing some intense stomach pains and vomiting; he didn’t think much of it as he thought he had a nasty stomach

We’re pleased to share a new resource designed to help patients and caregivers better understand bowel obstruction — what it is, why it happens, and how it’s evaluated and managed during cancer care. Bowel obstruction can be distressing and uncomfortable, especially for people with abdominal cancers, and having reliable information can help you feel more confident in navigating this challenge. What You’ll Learn This resource breaks down important, practical information into c

By Sarah Seitz Baltimore, Maryland In January 2023, I believed I was finally getting my life back. For years, my body had been in open rebellion against me. I lived with extreme abdominal pain, stabbing cramps that dropped me to the floor, fainting spells, overwhelming fatigue, and an inability to eat. I lost forty pounds in just a few months without trying. My periods were excruciating. I missed work, missed time with my family, and made more emergency room visits than I can

We are excited to share a new resource designed to help patients and caregivers navigate nutrition during cancer treatment, recovery, and through survivorship. Proper nourishment plays an important role in maintaining strength, supporting healing, managing side effects, and improving overall quality of life. This easy-to-use nutrition overview is tailored specifically to the challenges faced by people with abdominal cancers.

Predictors of Peritoneal Surface Recurrence and Quantitative Association with Time to Relapse After Complete CRS/HIPEC for Colorectal Peritoneal Metastasis. (2026). Cancers. 18. 299. DOI: 10.3390/cancers18020299 . Understanding Recurrence After CRS/HIPEC for Colorectal Cancer Spread to the Abdomen When colorectal cancer spreads to the lining of the abdomen (called peritoneal metastasis ), one treatment option for carefully selected patients is cytoreductive surgery (CRS) com

Pham ENB, Horeweg N, van der Marel J, Nooij LS. Survival benefit of cytoreductive surgery in patients with primary stage IV endometrial cancer: a systematic review & meta-analysis . BJC Rep. 2024 Oct 8;2(1):76. doi: 10.1038/s44276-024-00084-4 . PMID: 39516418; PMCID: PMC11523991. What Did the Study Look At? This research combined results from multiple published studies to find out whether cytoreductive surgery (CRS) — surgery that removes as much visible cancer as possible —

Phase II trial of systemic therapy plus intraperitoneal (IP) paclitaxel (PTX) in gastric/GEJ cancer peritoneal carcinomatosis (GPC): STOPGAP trial.

Falla-Zuniga LF, Sardi A, King MC, Lopez-Ramirez F, Kovalik V, Iugai S, Diaz-Montes T, Gushchin V. Small bowel obstruction and ovarian cancer: insights from a propensity-score matched study in patients with and without hyperthermic intraperitoneal chemotherapy after cytoreductive surgery. World J Surg Oncol. 2025 Aug 26;23(1):318. doi: 10.1186/s12957-025-03968-y. PMID: 40859247; PMCID: PMC12382003. Understanding the Study: Bowel Blockages in Advanced Ovarian Cancer This stu

By Antonia Dyroff Zurich, Switzerland The Challenge of Diagnosis and Isolation For many, a diagnosis of Pseudomyxoma Peritonei (PMP) is a life-altering event that changes one's world overnight. Upon discovering a large appendix tumor within the abdomen—a circumstance that seemed unimaginable—I underwent two major surgeries to remove the tumor and to manage the disease. Each operation presented a fierce physical and emotional battle, followed by a recovery process that was bot

This research study explored outcomes for people with colorectal cancer that had spread to two places at the same time: the lining of the abdomen (called the peritoneum), and the liver.

Safety and Efficacy of Cisplatin and Doxorubicin Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Patients with Ovarian Cancer with Peritoneal Metastases: A Multicenter US Phase I Trial. Authors : Nakamura, B., Senguttuvan, R., Ruel, N.H. et al. Ann Surg Oncol 33 , 415–425 (2026). https://doi.org/10.1245/s10434-025-18432-0 A New Way to Treat Cancer Spread in the Abdome n This study looked at a treatment called Pressurized Intra-Peritoneal Aerosol Chemother

Predictors of Successful Neoadjuvant Chemotherapy and Interval Cytoreductive Surgery in Management of Ovarian Cancer. ** Authors : Claudia Marchetti, MD, PhD, Gwenael Ferron, MD, et al. JCO Oncology Practice, Nov 24, 2025. DOI: 10.1200/OP-25-00469 Understanding Neoadjuvant Chemotherapy and Surgery What the Study Was About This study focused on individuals with ovarian cancer who receive neoadjuvant chemotherapy (NACT). This means they undergo chemotherapy before surgery. T

Efficacy and Safety of Secondary Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy in Platinum-Sensitive Recurrent Ovarian Cancer: A Systematic Review and Meta-Analysis Liu, HY., Tian, LH., Huang, G. et al. World J Surg Onc 23, 423 (2025). https://doi.org/10.1186/s12957-025-04076-7 What the Study Looked At Researchers examined data from over 1,100 individuals with platinum-sensitive recurrent ovarian cancer. This means their cancer initially responded to p

During November we recognized Gastric and Pancreatic Cancer Awareness Month to bring more attention to advanced forms of this cancer. In case you missed it, here's a quick recap for the month! Understanding Gastric Cancer: Risks, Outlook, and Advances Gastric cancer, also known as stomach cancer, is a rare and aggressive cancer that develops in the stomach, which is responsible for breaking down food during digestion. Most (90-95%) gastric cancers begin in the stomach’s inne

Controlling perfusion temperature relates to better outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Lopez-Ramirez, Felipe et al. European Journal of Surgical Oncology, Volume 52, Issue 1, 110536 What is HIPEC? HIPEC ( Hyperthermic Intraperitoneal Chemotherapy ) is a treatment where, after a surgeon removes as much visible tumor as possible (cytoreductive surgery), heated chemotherapy is circulated directly inside the abdominal cavity. Th

Appendix cancer is extremely rare — so rare that it does not appear in the American Cancer Society’s 2025 cancer statistics report and is listed by the National Institutes of Health under “rare digestive tumors.” Each year, only about 3,000 people in the U.S. are diagnosed. However, recent research shows that appendix cancer is becoming more common across all age groups. Dr. Shanel Bhagwandin, surgical oncologist and Medical Director of the Gastrointestinal Surgical Oncology