Risk Factors - Uterine and Endometrial Cancer Awareness Month
- Abdominal Cancers Alliance
- Jun 20
- 2 min read
Updated: Jun 23
Risk factors for Uterine and Endometrial cancers to be aware of include:
Uterine Cancer Risk Factors:
1️⃣ Age: Patients over 40
2️⃣ Ethnicity: African American women are frequently diagnosed
3️⃣ History of tamoxifen use >5 years
4️⃣ History of pelvic radiation therapy
5️⃣ Certain inherited syndromes and conditions (renal cell carcinoma, hereditary leiomyomatosis, retinoblastoma)
Endometrial Cancer Risk Factors:
1️⃣ Obesity: the strongest risk factor and linked to hormone changes
2️⃣ Age: Patients over 40
3️⃣ Ethnicity: African American women are frequently diagnosed
4️⃣ Type II Diabetes
5️⃣ Menopausal hormone therapy/Hormone-replacement drugs after menopause
6️⃣ Tamoxifen use 7️⃣ Family history of endometrial or colorectal cancer
8️⃣ History of breast or ovarian cancer
9️⃣ History of radiation therapy to the pelvis for another cancer
Prognosis for patients with uterine or endometrial cancers—especially when the disease has spread to the peritoneal cavity—depends largely on the extent of peritoneal involvement. When detected early, endometrial and uterine cancers are often highly treatable with surgery alone. However, treatment options may vary based on the tumor’s type, grade, and stage at diagnosis.
Most cases begin in the lining of the uterus and are addressed with surgical removal of the uterus and surrounding tissues. For rare or aggressive forms, such as uterine sarcoma, or in advanced-stage cases where cancer has spread beyond the uterus, additional therapies like chemotherapy or radiation may be required. In some cases, patients with peritoneal spread may benefit from Cytoreductive Surgery (CRS) with Hyperthermic Intraperitoneal Chemotherapy (HIPEC), depending on the cancer’s characteristics and location.
Early detection and specialized care are key.
Arm yourself—and your loved ones—with the information that matters.
Even the most proactive patients and advocates can only act on what they know. Help us spread the word about uterine and endometrial cancer!
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Come visit us on social media to follow along during the month of June to learn more about uterine and endometrial cancer and help spread the word!
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